کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2484985 | 1114342 | 2013 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The Use of Near-Infrared and Microwave Resonance Sensing to Monitor a Continuous Roller Compaction Process
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
اکتشاف دارویی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Roller compaction is commonly used in the pharmaceutical and nutraceutical industries to increase and narrow the size distribution of a particulate material, making it easier to process. Both the moisture content of the material and the density of the roller compacted ribbon affect the uniformity and physical properties of the resultant granules. Without process analytical technologies, these parameters cannot be determined on-line or in real time. In this study, the more commonly used near-infrared (NIR) spectroscopy was compared and contrasted with microwave resonance for the determination of roller-compacted ribbons' envelope density and moisture content. Results indicate that microwave resonance can offer improved accuracy, robustness, and ease-of-use compared with NIR spectroscopy for these property measurements. © 2013 Wiley Periodicals, Inc. and the American Pharmacists Association J Pharm Sci 102:1895-1904, 2013
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical Sciences - Volume 102, Issue 6, June 2013, Pages 1895-1904
Journal: Journal of Pharmaceutical Sciences - Volume 102, Issue 6, June 2013, Pages 1895-1904
نویسندگان
John Austin, Anshu Gupta, Ryan Mcdonnell, Gintaras V. Reklaitis, Michael T. Harris,