کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2485884 | 1114369 | 2007 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fluorescence Studies of the Dehydration of Cefadroxil Monohydrate*
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
اکتشاف دارویی
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چکیده انگلیسی
Although cefadroxil does not exhibit the phenomenon of photoluminescence when dissolved in a fluid medium, the compound has been found to exhibit fluorescence in its solidâstate monohydrate crystal form. The monohydrate was found to exhibit complicated photoluminescence, where two different sets of emission spectra could be obtained upon irradiation with an appropriate excitation wavelength. One of these photophysical systems became strongly suppressed when the monohydrate was halfâdehydrated, and only one of the photophysical systems could be observed in this hemihydrate. In the fully dehydrated state, both photophysical pathways became almost totally suppressed, so that the nonsolvated cefadroxil became effectively nonfluorescentand the American Pharmacists Association J Pharm Sci 96: 2757-2764, 2007
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical Sciences - Volume 96, Issue 10, October 2007, Pages 2757-2764
Journal: Journal of Pharmaceutical Sciences - Volume 96, Issue 10, October 2007, Pages 2757-2764
نویسندگان
Harry G. Brittain,