کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2486085 | 1114374 | 2010 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
First obtaining of glass solutions and phase diagram of glucose with fully tunable anomeric concentration
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
اکتشاف دارویی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: First obtaining of glass solutions and phase diagram of glucose with fully tunable anomeric concentration First obtaining of glass solutions and phase diagram of glucose with fully tunable anomeric concentration](/preview/png/2486085.png)
چکیده انگلیسی
In this article we show the possibility to form amorphous αâglucose/βâglucose molecular alloys directly in the solid state by comilling crystalline αâglucose and crystalline βâglucose. Contrary to the usual melt quenching process, milling does not induce any mutarotation so that alloys can be obtained for the whole range of anomeric concentration. This offers the unique possibility to explore the phase diagram of this binary system which appears to be a eutectic mixture. The structural and thermodynamic investigations have been performed by powder Xâray diffraction and differential scanning calorimetry. © 2009 WileyâLiss, Inc. and the American Pharmacists Association J Pharm Sci 99: 1476-1483, 2010
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pharmaceutical Sciences - Volume 99, Issue 3, March 2010, Pages 1476-1483
Journal: Journal of Pharmaceutical Sciences - Volume 99, Issue 3, March 2010, Pages 1476-1483
نویسندگان
N. Dujardin, J.F. Willart, E. Dudognon, F. Danède, M. Descamps,