The application of open disk-like structures as model membrane and drug carriers

The objective of this review is to outline the application of bicelles (or called bilayer micelles) and bilayer nanodisks in pharmaceutics, pharmaceutical analysis and biochemistry. The application of open disk-like structures as model membrane and drug carrier has been described. The exploration of many reports in different fields suggested that these open disk-like structures have great potential in studying interactions between drug-membrane and structure/function studies of membrane-bound proteins. Furthermore, they could be applied as promising carriers for in vivo delivery of drugs, protein and peptide.