کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2501364 | 1557336 | 2015 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Size analysis of nanoparticles extracted from W/O emulsions Size analysis of nanoparticles extracted from W/O emulsions](/preview/png/2501364.png)
Nanosized particles are frequently used in many different applications, especially TiO2 nanoparticles as physical filters in sunscreens to protect the skin from UV radiation. However, concerns have arisen about possible health issues caused by nanoparticles and therefore, the assessment of the occurrence of nanoparticles is important in pharmaceutical and cosmetic formulations. In a previous work of our group, a method was presented to extract nanoparticles from O/W emulsions. But to respond to the needs of dry and sensitive skin, sunscreens of the water-in-oil emulsion type are available. In these, assessment of present nanoparticles is also an important issue, so the present study offers a method for extracting nanoparticles from W/O emulsions. Both methods emanate from the same starting point, which minimizes both effort and cost before the beginning of the assessment. By addition of NaOH pellets and centrifugation, particles were extracted from W/O emulsions and measured for their size and surface area by laser diffraction. With the simple equation Q = A/S a distinction between nanoparticles and microparticles was achieved in W/O emulsions, even in commercially available samples. The present method is quick and easy to implement, which makes it cost-effective.
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Journal: International Journal of Pharmaceutics - Volume 488, Issues 1–2, 5 July 2015, Pages 29–32