کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2501611 | 1557348 | 2015 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Stability studies of As4S4 nanosuspension prepared by wet milling in Poloxamer 407 Stability studies of As4S4 nanosuspension prepared by wet milling in Poloxamer 407](/preview/png/2501611.png)
In this paper the stability of the arsenic sulfide (As4S4) nanosuspension prepared by wet milling in a circulation mill in the environment of copolymer Poloxamer 407 was studied. The obtained As4S4 particles in nanosuspension were of ∼100 nm in size. The influence of temperature and UV irradiation on the changes in physical and/or chemical properties was followed. Long-term stability was observed via particle size distribution and zeta potential measurements. Influence of UV irradiation was studied via UV–vis spectroscopy (UV–vis), photoluminicsence (PL) technique and Fourier transform infrared spectroscopy (FTIR) measurements. The best stability of the nanosuspension (24 weeks) was achieved when stored at 4 °C and in the dark.
Figure optionsDownload high-quality image (123 K)Download as PowerPoint slide
Journal: International Journal of Pharmaceutics - Volume 478, Issue 1, 15 January 2015, Pages 187–192