کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2503454 | 1557426 | 2011 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Endermatic, epidermatic, enepidermatic-The early history of penetration enhancers
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
علوم دارویی
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چکیده انگلیسی
Already at the end of the 18th century, attempts were made to administer drugs transdermally. Several techniques were applied, including rubbing drug substances into the intact or wounded skin. Penetration enhancers were investigated as well, including human and animal body fluids, in particular gastric juice and saliva. In the 19th century, lipophilic solubilizers like chloroform and ether were tried. Although the experiments were mostly done against a pre-rational background some may be worth to be judged under scientific premises.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pharmaceutics - Volume 416, Issue 1, 15 September 2011, Pages 12-15
Journal: International Journal of Pharmaceutics - Volume 416, Issue 1, 15 September 2011, Pages 12-15
نویسندگان
Axel Helmstädter,