کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2505181 1557479 2009 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی علوم دارویی
پیش نمایش صفحه اول مقاله
Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products
چکیده انگلیسی

Solid lipid nanoparticles (SLN) are distinguishable from nanostructured lipid carriers (NLC) by the composition of the solid particle matrix. Both are an alternative carrier system to liposomes and emulsions. This review paper focuses on lipid nanoparticles for dermal application. Production of lipid nanoparticles and final products containing lipid nanoparticles is feasible by well-established production methods. SLN and NLC exhibit many features for dermal application of cosmetics and pharmaceutics, i.e. controlled release of actives, drug targeting, occlusion and associated with it penetration enhancement and increase of skin hydration. Due to the production of lipid nanoparticles from physiological and/or biodegradable lipids, this carrier system exhibits an excellent tolerability. The lipid nanoparticles are a “nanosafe” carrier. Furthermore, an overview of the cosmetic products currently on the market is given and the improvement of the benefit/risk ratio of the topical therapy is shown.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pharmaceutics - Volume 366, Issues 1–2, 21 January 2009, Pages 170–184
نویسندگان
, , ,