کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2506268 1557512 2007 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effect of monomers on the formulation of polymeric nanocapsules based on polyureas and polyamides
موضوعات مرتبط
علوم پزشکی و سلامت داروسازی، سم شناسی و علوم دارویی علوم دارویی
پیش نمایش صفحه اول مقاله
The effect of monomers on the formulation of polymeric nanocapsules based on polyureas and polyamides
چکیده انگلیسی

Formulation of nanocapsules based on polyureas and polyamides have been tested using a patented process. This method based on polycondensation reaction of two complementary monomers and spontaneous formation of oil in water emulsion, is an alternative concept to the known technique based on the same type of reaction used for the formulation of microcapsules, and in which the lipophilic monomer was emulsified in the organic phase before the formation of the polymeric membrane. Nanocapsules can be prepared from different monomers. Wall based on cross-linked polymer contributes to the stability of nanocapsules during and after formulation. The permeability of the polymeric wall is related to its crystallinity and contributes to the growth of nanocapsule membrane by the diffusion of the hydrophilic monomers to get stable colloidal suspensions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pharmaceutics - Volume 335, Issues 1–2, 20 April 2007, Pages 176–179
نویسندگان
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