کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2506583 | 1557526 | 2006 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Microencapsulation of drugs by electro-hydro-dynamic atomization
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
علوم دارویی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Microencapsulation of drugs by electro-hydro-dynamic atomization Microencapsulation of drugs by electro-hydro-dynamic atomization](/preview/png/2506583.png)
چکیده انگلیسی
This paper presents practical aspects of production of polymeric particles loaded with a drug by electro-hydro-dynamic atomization (EHDA). Particles were produced from paracetamol (4-acetamidophenol), budesonide and polylactic acid containing Taxol (paclitaxel). Influence of solvent type and evaporation rate, as well as other polymers additives on particle morphology and drug release rate is demonstrated. It is shown that quickly evaporating solvents have a tendency to form hollow particles. Drug release rate from hollow particles is substantially higher than from solid ones. Addition of water-soluble polymer, polyethylene glycol, also increases drug release rate.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Pharmaceutics - Volume 324, Issue 1, 31 October 2006, Pages 51–55
Journal: International Journal of Pharmaceutics - Volume 324, Issue 1, 31 October 2006, Pages 51–55
نویسندگان
Tomasz Ciach,