کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2509415 | 1117663 | 2015 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Preparation and in vitro evaluation of enteric-coated tablets of rosiglitazone sodium Preparation and in vitro evaluation of enteric-coated tablets of rosiglitazone sodium](/preview/png/2509415.png)
The aim of this study was to prepare the rosiglitazone sodium enteric-coated tablets and investigate its release rate. The rosiglitazone sodium enteric-coated tablet was prepared by single punch tablet press using substituted hydroxypropyl cellulose and polyvinylpyrrolidone (PVP). The release rate from the enteric-coated tablet of rosiglitazone sodium was evaluated. The release rate study showed that few rosiglitazone sodium was released from enteric coated formulation within 2 h in simulated gastric juice, while it released more than 80% of the labeled amount in 30 min in simulated intestinal juice. The preparing method of rosiglitazone sodium enteric-coated tablets was simple and had a good reproducibility. The release condition and determined methods could be used for the routine determinations of rosiglitazone sodium enteric-coated tablets.
Journal: Saudi Pharmaceutical Journal - Volume 23, Issue 5, October 2015, Pages 581–586