کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2511539 1557846 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Herpesvirus latency and therapy—From a veterinary perspective
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ویروس شناسی
پیش نمایش صفحه اول مقاله
Herpesvirus latency and therapy—From a veterinary perspective
چکیده انگلیسی

This short review considers how the human herpesviruses were among the first viruses to be effectively treated by means of antiviral therapy although the ability of alphaherpsviruses to establish neuronal latency with reactivation remains the major obstacle to achieving a cure. Laboratory animals played an essential role in the development of herpes antivirals including our understanding of the complexity of the neurological infection in relation to chemotherapy. The existence of natural herpesvirus infections in domestic species also contributes to our understanding of latency and reactivation relevant to antiviral therapy although the use of antivirals to treat or prevent virus infections in veterinary species has been minimal, to date. The review briefly focuses on herpes infections in the horse and cat where some progress has already been achieved in the veterinary antiviral field.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Antiviral Research - Volume 71, Issues 2–3, September 2006, Pages 127–133
نویسندگان
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