کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2525642 1119621 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modelling the interaction of haemodynamics and the artery wall: Current status and future prospects
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Modelling the interaction of haemodynamics and the artery wall: Current status and future prospects
چکیده انگلیسی

Clinical research has historically focused on the two main strategies of in vivo and in vitro experimentation. The concept of applying scientific theory to direct clinical applications is relatively recent. In this paper we focus on the interaction of wall shear stress with the endothelium and discuss how ‘state of the art’ computer modelling techniques can provide valuable data to aid understanding. Such data may be used to inform experiment and further, may help identify the key features of this complex system. Current emphasis is on coupling haemodynamics with models of biological phenomena to test hypotheses or predict the likely outcome of a disease or an intervention. New technologies to enable the integration of models of different types, levels of complexity and scales, are being developed. As will be discussed, the ultimate goal is the translation of this technology to the clinical arena.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 62, Issue 8, October 2008, Pages 530–535
نویسندگان
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