کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2525643 1119621 2008 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hemodynamic parameters regulating vascular inflammation and atherosclerosis: A brief update
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Hemodynamic parameters regulating vascular inflammation and atherosclerosis: A brief update
چکیده انگلیسی

Atherosclerosis is a chronic lipid-driven inflammatory disease of the arteries. Early lesions (fatty streaks) contain monocytes and T lymphocytes which are recruited from the circulation by adhesion to activated vascular endothelial cells (EC). This process is described as the leukocyte adhesion cascade. Atherogenesis occurs predominantly at branches and bends of the arterial tree that are exposed to relatively low or re-circulating blood flow. Here we briefly review the effects of blood flow and shear stress on the leukocyte adhesion cascade and endothelial cell function.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 62, Issue 8, October 2008, Pages 536–540
نویسندگان
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