Engineered heart tissue transplantation alters electrical-conduction function in rats with myocardial infarction

AimsTo investigate how affects electrical-conduction function following myocardial infarction (MI) in rats.Main methodsThirty SD rats of either sex (220–250 g) were anesthetized using chlorine hydrate and were randomly divided into three groups: control group, MI group and transplantation group. The field potential (FP) morphology and activation–conduction duration were recorded with microeletrode array techniques.Key findingsThe MEA recorded clear FP morphology. Activation–conduction duration was (6.5 ± 2.12) ms in the control group, (17.5 ± 3.54) ms in the MI group, and (9.13 ± 1.31) ms in the transplantation group.SignificanceEHT transplantation can improve electrical-conduction and function of MI rats.