کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2551727 1560638 2012 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Presence of ChAT mRNA and a very marked α7nAChR immunoreaction in the synovial lining layer of the knee joint
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Presence of ChAT mRNA and a very marked α7nAChR immunoreaction in the synovial lining layer of the knee joint
چکیده انگلیسی
There is a potential for ACh production within the synovial lining layer as there are ChAT mRNA reactions. However, the level of ACh production is apparently very low. It is thus possible that there is a down-regulation of ACh production but an apparent upregulation in expression level of α7nAChR. Based on the knowledge that the non-neuronal cholinergic system can have anti-inflammatory effects, the low level of ACh production in the synovial lining layer can be a drawback for the arthritic joints.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Life Sciences - Volume 91, Issues 21–22, 27 November 2012, Pages 1043-1047
نویسندگان
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