کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2552204 1560692 2010 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Extracellular matrix roles during cardiac repair
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Extracellular matrix roles during cardiac repair
چکیده انگلیسی

The cardiac extracellular matrix (ECM) provides a platform for cells to maintain structure and function, which in turn maintains tissue function. In response to injury, the ECM undergoes remodeling that involves synthesis, incorporation, and degradation of matrix proteins, with the net outcome determined by the balance of these processes. The major goals of this review are a) to serve as an initial resource for students and investigators new to the cardiac ECM remodeling field, and b) to highlight a few of the key exciting avenues and methodologies that have recently been explored. While we focus on cardiac injury and responses of the left ventricle (LV), the mechanisms reviewed here have pathways in common with other wound healing models.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Life Sciences - Volume 87, Issues 13–14, 25 September 2010, Pages 391–400
نویسندگان
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