کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2565336 | 1128056 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The integrity of corpus callosum and cluster B personality disorders: A quantitative MRI study in juvenile myoclonic epilepsy
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کلمات کلیدی
DSMIgEROIidiopathic generalized epilepsiesVBMGTCSCorpus callosumJMEPersonality disorders - اختلال شخصیتElectroencephalogram - الکتروانسفالوگرافیILAE - ایلاgeneralized tonic–clonic seizures - تشنجهای تونیک کلونیک تعمیم یافتهJuvenile myoclonic epilepsy - صرع مایوکلونیک نوجوانانInternational League against Epilepsy - لیگ بین المللی علیه صرعRegions Of Interest - مناطق مورد علاقهvoxel-based morphometry - مورفومتری مبتنی بر واکسلEEG - نوار مغزی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Evidence suggests increased prevalence of cluster B personality disorders (PD) among patients with juvenile myoclonic epilepsy (JME), which has been associated with worse seizure control and more psychosocial dysfunctions. A preliminary voxel-based morphometry study demonstrated corpus callosum (CC) volume reduction in patients with JME and cluster B PD, particularly in the posterior midbody and isthmus. In this study we aimed to follow up these results with region of interest analysis. Sixteen JME patients with cluster B PD, 38 JME patients without any psychiatric disorder, and 30 demographically matched healthy controls submitted to a psychiatric evaluation and a magnetic resonance imaging scan. The total and regional callosal areas were obtained from the midsagittal slice using a semi-automated program. Psychiatric evaluation was performed through SCID-I and -II. Significant reductions in the posterior region of the CC were observed in the JME with PD group relative to the other groups. These data support previous findings of callosal reductions in cluster B PD, as well as a possible involvement of CC in patients with JME and such personality characteristics.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 34, Issue 3, 16 April 2010, Pages 516-521
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 34, Issue 3, 16 April 2010, Pages 516-521
نویسندگان
Gerardo Maria de Araújo Filho, Andrea Parolin Jackowski, Katia Lin, Ivaldo Silva, Mirian S.B. Guaranha, Laura M.F.F. Guilhoto, Henrique Carrete Júnior, Elza Márcia T. Yacubian, Rodrigo Affonseca Bressan,