کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2565858 | 1128068 | 2008 | 4 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Yi-gan san for the treatment of neuroleptic-induced tardive dyskinesia: An open-label study Yi-gan san for the treatment of neuroleptic-induced tardive dyskinesia: An open-label study](/preview/png/2565858.png)
BackgroundRecent studies indicate that the traditional Japanese herbal medicine yi-gan san (YGS, yokukan-san in Japanese), a serotonin modulator, may be safe and useful in treating behavioral and psychological symptoms in dementia and borderline personality disorder patients. The authors examined the efficacy, tolerability, and safety of YGS in patients with tardive dyskinesia.MethodsTwenty-two patients with schizophrenia who had neuroleptic-induced tardive dyskinesia were given 7.5 g/day of YGS for 12 weeks in an open-label study.ResultsAdministration of YGS resulted in a statistically significant improvement in tardive dyskinesia and psychotic symptoms.ConclusionsYGS may be an effective and safe therapy to control tardive dyskinesia and psychosis in patients with schizophrenia, that should be further tested in double-blind, placebo-controlled trials.
Journal: Progress in Neuro-Psychopharmacology and Biological Psychiatry - Volume 32, Issue 3, 1 April 2008, Pages 761–764