کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2592769 1132045 2008 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A review of critical factors in the conduct and interpretation of the human repeat insult patch test
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
A review of critical factors in the conduct and interpretation of the human repeat insult patch test
چکیده انگلیسی

This paper reviews key factors that are critical to the conduct and interpretation of Human Repeat Insult Patch Tests (HRIPTs). A methodology for HRIP testing is described and general guidelines for evaluation of responses indicative of induction and elicitation of skin sensitization and skin irritation are detailed. Understanding and applying these key factors is crucial to the design of such studies and reliability of the resulting data when used in the overall risk assessment process.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Regulatory Toxicology and Pharmacology - Volume 52, Issue 1, October 2008, Pages 24–34
نویسندگان
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