کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2598347 1562618 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Comparative study of oxidative stress biomarkers in urine of cooks exposed to three types of cooking-related particles
ترجمه فارسی عنوان
بررسی مقایسه ای بیومارکرهای استرس اکسیداتیو در ادرار آشپز در معرض سه نوع ذرات مرتبط با پخت و پز
کلمات کلیدی
روغن های سرخ کرده تکراری زباله های رستوران، ذرات جامد، هیدروکربن آروماتیک چند حلقه ای، مالون دی آلدئید، 8-هیدروکسی-2'-دگزسی گوانوزین
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی


• Higher UFP, PM2.5 and PAHs exposure in cookers.
• Urinary 1-OHP, MDA and 8-OHdG reflect COFs exposure.
• RFO may cause increased oxidative DNA damage.
• RWO may cause increased lipid peroxidation.

ObjectivesTo evaluate how exposure to deep-frying oils, repeated frying oil (RFO) and restaurant waste oil (RWO) affects emission of polycyclic aromatic hydrocarbons (PAHs) and oxidative stress in male restaurant workers.MethodsThe study participants included 236 male restaurant workers in 12 restaurants in Shenzhen. Airborne particulate PAHs were measured over 12 h on each of two consecutive work days. Urinary 1-hydroxypyrene (1-OHP) measurements were used to indicate cooking oil fumes (COF) exposure, and urinary malondialdehyde (MDA) and 8-hydroxy-2′-deoxyguanosine (8-OHdG) were adopted as oxidative stress markers.ResultsThe production and emission rates of ultrafine particles (UFPs) and PM2.5 were higher in the exposed groups than in the control group. The concentrations of summed PAHs were in the order of RFO-frying group > RWO-frying group > deep-frying group > unexposed control group. Urinary 1-OHP was found to be a significant predictor of elevated urinary MDA and 8-OHdG concentrations (all, P < 0.05). UFPs were a significant predictor of elevated urinary 8-OHdG for restaurant workers (P < 0.05). The RFO- and RWO-frying groups had higher mean urinary concentrations of 1-OHP, MDA and 8-OHdG than the control group (P < 0.05). RFO exposure was found to be a significant risk factor for elevated urinary 8-OHdG and RWO exposure was found to be a significant risk factor for elevated urinary MDA (both, P < 0.001).ConclusionsConcentrations of urinary 1-OHP, MDA and 8-OHdG reflect occupational exposure to PAHs from COFs and oxidative stress in restaurants workers. Exposure to RFO may cause increased oxidative DNA damage, and exposure to RWO might cause increased lipid peroxidation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology Letters - Volume 255, 25 July 2016, Pages 36–42
نویسندگان
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