Photocatalytic organic syntheses using a glass-milled microchip

• A glass-milled microchip is proposed for photocatalytic organic syntheses.
• Oxidation and reduction reactions for aromatic compounds are demonstrated.
• Imine is synthesized using a multi-step reaction.
• Photocatalytic microchip can be used more than 300 times.

Photocatalytic reactions, typically known as difficult to control due to secondary reactions and involvement of multiple radicals, were demonstrated to be controlled well by optimizing the reaction time and the microchip design. The glass-milled microchip has a good resistivity for the organic solutions and withstands multiple usage more than 100 times. The oxidization and reduction reactions were demonstrated and the flow considerably improved the conversion and yield. Furthermore, an imine synthesis was demonstrated as a multi-step reaction by combination of photocatalytic oxidation and reduction reactions.

A glass-milled microchip is proposed for photocatalytic organic syntheses, which could be used more than 300 times, and oxidation and reduction reactions for aromatic compounds, multi-step reaction for imine synthesis were demonstrated.Figure optionsDownload as PowerPoint slide