کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2785021 | 1153925 | 2009 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Genetic variation of regulatory systems
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Genetic variation of regulatory systems Genetic variation of regulatory systems](/preview/png/2785021.png)
چکیده انگلیسی
The regulation of gene expression is one of the most important cellular functions that determines developmental and somatic cell fates. Studies that attempt to describe the molecular interactions that govern gene regulation highlight the complexity and multidimensionality of this process. The recent explosion of information on genetic variation has added yet another dimension to this complexity. Genetic variation in elements that control gene expression directly or indirectly through interactions with other elements or molecules, contributes to observed expression level differences between individuals of the same species. In this short review we will address some of the key principles of the past and recent studies describing the degree and nature of regulatory variation with a focus on human populations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Genetics & Development - Volume 19, Issue 6, December 2009, Pages 586-590
Journal: Current Opinion in Genetics & Development - Volume 19, Issue 6, December 2009, Pages 586-590
نویسندگان
Antigone S Dimas, Emmanouil T Dermitzakis,