کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2785252 | 1153937 | 2006 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Transcriptional control thrown for a loop
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
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چکیده انگلیسی
The relationships among in vivo chromatin structures, chromosome organization and genome function must be understood in order to reveal the hidden regulatory information in our genomes. Rather than being stable architectural features, it appears that chromatin and chromosome conformations at all levels are highly dynamic, which is the key to their function. Studies in recent years have elucidated long-range interactions or folded chromatin conformations that play significant roles in gene regulation. Most recently, intrachromosomal associations and co-associations with shared nuclear transcription compartments have been discovered in mammals, with the potential to greatly expand our view of how the genome is regulated.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Genetics & Development - Volume 16, Issue 5, October 2006, Pages 490–495
Journal: Current Opinion in Genetics & Development - Volume 16, Issue 5, October 2006, Pages 490–495
نویسندگان
Peter Fraser,