کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2785330 | 1153941 | 2008 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Genomics and the evolutionary origins of nervous system complexity
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
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چکیده انگلیسی
Advances in genomics are leading to increased understanding of the evolution of complexity, especially by beginning to bridge genotype and phenotype. Here, using examples from nervous system evolution, we define general patterns of increased complexity seen across levels of biological organization. We also explore specific evolutionary mechanisms that increase complexity, namely those that increase the number of biological units (parts) in a system. We provide specific neurobiological examples of increased complexity in genes, gene networks, cell types, and tissues/organs. These examples illustrate that while a variety of different mechanisms increase biological complexity, they can be understood in a generalized comparative framework.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Genetics & Development - Volume 18, Issue 6, December 2008, Pages 479–492
Journal: Current Opinion in Genetics & Development - Volume 18, Issue 6, December 2008, Pages 479–492
نویسندگان
Todd H Oakley, Ajna S Rivera,