کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2785458 | 1153954 | 2007 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Narcolepsy and familial advanced sleep-phase syndrome: molecular genetics of sleep disorders
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Narcolepsy and familial advanced sleep-phase syndrome: molecular genetics of sleep disorders Narcolepsy and familial advanced sleep-phase syndrome: molecular genetics of sleep disorders](/preview/png/2785458.png)
چکیده انگلیسی
Sleep disorders are very prevalent and represent an emerging worldwide epidemic. However, research into the molecular genetics of sleep disorders remains surprisingly one of the least active fields. Nevertheless, rapid progress is being made in several prototypical disorders, leading recently to the identification of the molecular pathways underlying narcolepsy and familial advanced sleep-phase syndrome. Since the first reports of spontaneous and induced loss-of-function mutations leading to hypocretin deficiency in human and animal models of narcolepsy, the role of this novel neurotransmission pathway in sleep and several other behaviors has
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Genetics & Development - Volume 17, Issue 3, June 2007, Pages 222–227
Journal: Current Opinion in Genetics & Development - Volume 17, Issue 3, June 2007, Pages 222–227
نویسندگان
Mehdi Tafti, Yves Dauvilliers, Sebastiaan Overeem,