کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2796399 1155598 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The relationship between central hemodynamics, morning blood pressure surge, glycemic control and sodium intake in patients with type 2 diabetes and essential hypertension
ترجمه فارسی عنوان
ارتباط بین همودینامیک مرکزی، افزایش فشار خون صبح، کنترل گلیسمی و مصرف سدیم در بیماران مبتلا به دیابت نوع 2 و فشار خون بالا
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی

AimsThe current study aimed to investigate the relationship between morning blood pressure surge (MBPS), hemodynamic parameters, glycemic control and 24-h urinary sodium excretion (USE) in patients with type 2 diabetes mellitus (T2DM).Materials and methodsMBPS and central hemodynamic parameters were assessed from ambulatory blood pressure measurements. In addition to routine biochemistry, 24 h urine collection was performed to measure protein, albumin and sodium excretion.ResultsThere were 146 (38%) patients with T2DM and 238 (72%) patients without T2DM (control group). Patients with T2DM had statistically higher MBPS compared with patients without T2DM (P < 0.0001). In patients with T2DM, MBPS was correlated with HbA1c (rho = 0.311, P < 0.0001), 24 h urinary sodium excretion (USE) (rho = 0.292, P = 0.004) and various hemodynamic parameters. Additionally, regression analysis showed that being male (P = 0.006), the presence of coronary artery disease (P = 0.023), HbA1c (P = 0.012), and 24 h USE (P = 0.001) were independently related with log MBPS in T2DM patients.ConclusionThis study demonstrated that T2DM was an independent risk factor for increased MBPS and MBPS was associated with central hemodynamic parameters. Additionally poor glycemic control and sodium intake were associated with worse MBPS in T2DM.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 104, Issue 3, June 2014, Pages 420–426
نویسندگان
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