کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2797874 | 1155669 | 2009 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fine-tuning of prediction of isolated impaired glucose tolerance: A quantitative clinical prediction model
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کلمات کلیدی
TLGSIGTRPMNHANES IIISBPFPGDBPIFGLDL-CHDL-COral glucose tolerance test (OGTT) - آزمون تحمل گلوکز خوراکی (OGTT)impaired glucose tolerance - اختلال تحمل گلوکزImpaired fasting glucose - اختلال قندخون ناشتاcardiovascular disease - بیماری قلب و عروقیTriglycerides - تریگلیسریدDiagnosis - تشخیصDiabetes mellitus - دیابت قندیCVD - رسوب دهی شیمیایی بخار Decode - رمزگشاییThird National Health and Nutrition Examination Survey - سومین بررسی ملی بهداشت و تغذیهPrevalence - شیوعScreening - غربالگریdiastolic blood pressure - فشار خون دیاستولیکsystolic blood pressure - فشار خون سیستولیکFasting plasma glucose - قند خون ناشتاhigh-density lipoprotein cholesterol - لیپوپروتئین پرچگالی یا اچدیالTehran Lipid and Glucose Study - مطالعه لیپید تهران و قند خونLikelihood ratio - نسبت احتمالtotal cholesterol - کلسترول تامLow-density lipoprotein cholesterol - کلسترول لیپوپروتئین با چگالی کم
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
علوم غدد
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In this cross-sectional study, we evaluated results of oral glucose tolerance test (OGTT) from 4742 women and 3470 men, participated in the Tehran Lipid and Glucose Study, aged â¥20 years and without diabetes, to determine the diagnostic value of subjects' clinical traits with isolated impaired glucose tolerance (isolated-IGT) defined as fasting plasma glucose (FPG) <5.6 mmol/L and 2-h plasma glucose between 7.8 and 11.1 mmol/L. The overall prevalence of IGT was 13.6% (n = 1120); of these subjects, 59.6% (n = 668) had isolated-IGT. The adjusted odds ratios for having isolated-IGT among 7012 subjects with FPG <5.6 mmol/L were significant for age â¥40 years (2.5), hypertension (1.9), abnormal waist circumference (1.9), obesity (1.5), and family history of diabetes (1.3). Adding the lipid profiles to the clinical model increased the area under the ROC curve only slightly (73.2% vs. 72.1%, respectively; P = 0.002). In summary, this study showed that in adults with FPG <5.6 mmol/L, older age, family history of diabetes, abnormal waist circumference and obesity, and hypertension were significantly associated with a higher likelihood of isolated-IGT; OGTT could hence be recommended in subjects who have most of these characteristics to find Isolated-IGT, especially if the findings are supported by appropriately designed clinical trials.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 83, Issue 1, January 2009, Pages 61-68
Journal: Diabetes Research and Clinical Practice - Volume 83, Issue 1, January 2009, Pages 61-68
نویسندگان
Mehdi Rambod, Farhad Hosseinpanah, Emad M. Ardakani, Mojgan Padyab, Fereidoun Azizi,