کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2798248 1568808 2008 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Metabolic risk factors, insulin-resistance and lifestyle in children of type 2 diabetes patients in Karachi, Pakistan
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
پیش نمایش صفحه اول مقاله
Metabolic risk factors, insulin-resistance and lifestyle in children of type 2 diabetes patients in Karachi, Pakistan
چکیده انگلیسی

AimsTo assess metabolic risk factors, insulin-resistance and lifestyle in children aged 8–20 years of patients with type 2 diabetes and to compare these with children aged 8–20 years of non-diabetic subjects.MethodsCase–control study. Data were collected from 37 children/adolescents of type 2 diabetes patients and 37 controls from parents without diabetes. Variables included physical activity, diet, socioeconomic class, family history, ethnic background, anthropometric measures, blood pressure and fasting glucose and insulin.ResultsGroups were comparable for age and gender. Differences between cases and controls were found for BMI (22.6 vs. 19.1 kg/m2, p = 0.004), waist circumference (70.1 vs. 62.1 cm, p = 0.014), systolic blood pressure (104.5 ± 15.1 vs. 97.9 ± 13.4 mmHg, p = 0.05), diastolic blood pressure (66.2 ± 10.9 vs. 60.7 ± 10.1 mmHg, p = 0.025).Vegetable intake (3% of cases having two and 19% one full serving a day vs., respectively, 14% and 32% amongst controls, p = 0.01) was less favourable in cases, and physical activity tended to be (5 h vs. 9 h/week, p = 0.065).ConclusionsChildren of type 2 diabetes patients have higher BMI and blood pressure than controls but also lead a less healthy lifestyle. This suggests that both genetic and lifestyle factors contribute to the increased risk of metabolic syndrome in children and early preventive measures towards changing lifestyle could help in prevention.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diabetes Research and Clinical Practice - Volume 80, Issue 3, June 2008, Pages 399–404
نویسندگان
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