کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2820631 | 1160872 | 2015 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Secondary structure-based analysis of mouse brain small RNA sequences obtained by using next-generation sequencing
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
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چکیده انگلیسی
• NGS was applied to small RNA fractions with 40 to 140 nt.
• Secondary structure-based clustering was performed.
• 16 candidate mouse structured small non-coding RNAs (MsncRs) were isolated.
In order to find novel structured small RNAs, next-generation sequencing was applied to small RNA fractions with lengths ranging from 40 to 140 nt and secondary structure-based clustering was performed. Sequences of structured RNAs were effectively clustered and analyzed by secondary structure. Although more than 99% of the obtained sequences were known RNAs, 16 candidate mouse structured small non-coding RNAs (MsncRs) were isolated. Based on these results, the merits of secondary structure-based analysis are discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Genomics - Volume 106, Issue 2, August 2015, Pages 122–128
Journal: Genomics - Volume 106, Issue 2, August 2015, Pages 122–128
نویسندگان
Hidenori Kiyosawa, Akio Okumura, Saya Okui, Chisato Ushida, Gota Kawai,