کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2821290 | 1160939 | 2007 | 9 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes hORFeome v3.1: A resource of human open reading frames representing over 10,000 human genes](/preview/png/2821290.png)
Complete sets of cloned protein-encoding open reading frames (ORFs), or ORFeomes, are essential tools for large-scale proteomics and systems biology studies. Here we describe human ORFeome version 3.1 (hORFeome v3.1), currently the largest publicly available resource of full-length human ORFs (available at www.openbiosystems.com). Generated by Gateway recombinational cloning, this collection contains 12,212 ORFs, representing 10,214 human genes, and corresponds to a 51% expansion of the original hORFeome v1.1. An online human ORFeome database, hORFDB, was built and serves as the central repository for all cloned human ORFs (http://horfdb.dfci.harvard.edu). This expansion of the original ORFeome resource greatly increases the potential experimental search space for large-scale proteomics studies, which will lead to the generation of more comprehensive datasets.
Journal: Genomics - Volume 89, Issue 3, March 2007, Pages 307–315