کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2822606 1161300 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Wavelet Analysis of DNA Walks on the Human and Chimpanzee MAGE/CSAG-palindromes
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
Wavelet Analysis of DNA Walks on the Human and Chimpanzee MAGE/CSAG-palindromes
چکیده انگلیسی

The palindrome is one class of symmetrical duplications with reverse complementary characters, which is widely distributed in many organisms. Graphical representation of DNA sequence provides a simple way of viewing and comparing various genomic structures. Through 3-D DNA walk analysis, the similarity and differences in nucleotide composition, as well as the evolutionary relationship between human and chimpanzee MAGE/CSAG-palindromes, can be clearly revealed. Further wavelet analysis indicated that duplicated segments have irregular patterns compared to their surrounding sequences. However, sequence similarity analysis suggests that there is possible common ancestor between human and chimpanzee MAGE/CSAG-palindromes. Based on the specific distribution and orientation of the repeated sequences, a simple possible evolutionary model of the palindromes is suggested, which may help us to better understand the evolutionary course of the genes and the symmetrical sequences.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Genomics, Proteomics & Bioinformatics - Volume 10, Issue 4, August 2012, Pages 230–236
نویسندگان
, , ,