کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2824916 1161882 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The faster-X effect: integrating theory and data
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
پیش نمایش صفحه اول مقاله
The faster-X effect: integrating theory and data
چکیده انگلیسی


• Differences between X chromosomes and autosomes illuminate the process of adaptation.
• Theory predicts that X-linked genes evolve faster than do autosomal genes.
• The evidence for the faster evolution of X-linked genes is mixed.
• New theory and data analysis are needed to bridge this divide.

Population genetics theory predicts that X (or Z) chromosomes could play disproportionate roles in speciation and evolutionary divergence, and recent genome-wide analyses have identified situations in which X or Z-linked divergence exceeds that on the autosomes (the so-called ‘faster-X effect’). Here, we summarize the current state of both the theory and data surrounding the study of faster-X evolution. Our survey indicates that the faster-X effect is pervasive across a taxonomically diverse array of evolutionary lineages. These patterns could be informative of the dominance or recessivity of beneficial mutations and the nature of genetic variation acted upon by natural selection. We also identify several aspects of disagreement between these empirical results and the population genetic models used to interpret them. However, there are clearly delineated aspects of the problem for which additional modeling and collection of genomic data will address these discrepancies and provide novel insights into the population genetics of adaptation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 29, Issue 9, September 2013, Pages 537–544
نویسندگان
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