کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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2825541 | 1161958 | 2008 | 8 صفحه PDF | دانلود رایگان |
Two empirical rules suggest that sex chromosomes play a special role in speciation. The first is Haldane's rule – the preferential sterility and inviability of species hybrids of the heterogametic (XY) sex. The second is the disproportionately large effect of the X chromosome in genetic analyses of hybrid sterility. Whereas the causes of Haldane's rule are well established, the causes of the ‘large X-effect’ have remained controversial. New genetic analyses in Drosophila confirm that the X is a hotspot for hybrid male sterility factors, providing a proximate explanation for the large X-effect. Several other new findings – on faster X evolution, X chromosome meiotic drive and the regulation of the X chromosome in the male-germline – provide plausible evolutionary explanations for the large X-effect.
Journal: - Volume 24, Issue 7, July 2008, Pages 336–343