کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2826590 1162251 2006 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
trans meets cis in MADS science
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
trans meets cis in MADS science
چکیده انگلیسی

The interaction between a transcription factor and its binding site at the DNA is an integral part of transcriptional regulatory networks, which is fundamental for an understanding of biological processes. An example is the family of MADS domain transcription factors, which represent key regulators of processes in yeast, animals and plants. However, despite our extensive knowledge of these transcription factors, limited information is available on the cis-elements to which these proteins bind or how these elements are defined. Here, we discuss the current understanding of MADS protein binding sites and compare data from various organisms. This information can help us in developing algorithms to predict binding sites for MADS domain transcription factors, which would be a significant step forward in the identification of ‘down-stream’ target genes and the elucidation of transcriptional networks.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: - Volume 11, Issue 5, May 2006, Pages 224–231
نویسندگان
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