Correction of iodine-123-labeled meta-iodobenzylguanidine uptake with multi-window methods for standardization of the heart-to-mediastinum ratio

The H/M ratio with the ME collimator, after application of the TEW or IDW methods, was close to the theoretical value in the phantom study. However, the corrected H/M ratios with the LEHR collimator provided comparable H/M ratios to the uncorrected ME data in phantom and clinical studies.