کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3000083 | 1180316 | 2010 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Peripheral Artery Disease: Current Insight Into the Disease and Its Diagnosis and Management
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کلمات کلیدی
CTAACEABILDL-CNHANESMRAMyocardial infarction - آنفارکتوس میوکاردAngiotensin-converting enzyme - آنژیوتانسین تبدیل آنزیمcomputed tomographic angiography - آنژیوگرافی توموگرافی کامپیوتریMagnetic resonance angiography - آنژیوگرافی رزونانس مغناطیسیNational Health and Nutrition Examination Survey - بررسی بهداشت و تغذیه ملیPeripheral artery disease - بیماری شریانی محیطیcoronary artery disease - بیماری عروق کرونرankle brachial index - شاخص پروگزیمال مچ پاCAD - طراحی به کمک رایانه یا کَدconfidence interval - فاصله اطمینانPAD - پدLow-density lipoprotein cholesterol - کلسترول لیپوپروتئین با چگالی کم
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Peripheral artery disease (PAD), which comprises atherosclerosis of the abdominal aorta, iliac, and lower-extremity arteries, is underdiagnosed, undertreated, and poorly understood by the medical community. Patients with PAD may experience a multitude of problems, such as claudication, ischemic rest pain, ischemic ulcerations, repeated hospitalizations, revascularizations, and limb loss. This may lead to a poor quality of life and a high rate of depression. From the standpoint of the limb, the prognosis of patients with PAD is favorable in that the claudication remains stable in 70% to 80% of patients over a 10-year period. However, the rate of myocardial infarction, stroke, and cardiovascular death in patients with both symptomatic and asymptomatic PAD is markedly increased. The ankle brachial index is an excellent screening test for the presence of PAD. Imaging studies (duplex ultrasonography, computed tomographic angiography, magnetic resonance angiography, catheter-based angiography) may provide additional anatomic information if revascularization is planned. The goals of therapy are to improve symptoms and thus quality of life and to decrease the cardiovascular event rate (myocardial infarction, stroke, cardiovascular death). The former is accomplished by establishing a supervised exercise program and administering cilostazol or performing a revascularization procedure if medical therapy is ineffective. A comprehensive program of cardiovascular risk modification (discontinuation of tobacco use and control of lipids, blood pressure, and diabetes) will help to prevent the latter.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 85, Issue 7, July 2010, Pages 678-692
Journal: Mayo Clinic Proceedings - Volume 85, Issue 7, July 2010, Pages 678-692
نویسندگان
Jeffrey W. DO, Brett A. MD,