کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3000338 | 1180327 | 2007 | 19 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Treatment of Newly Diagnosed Multiple Myeloma Based on Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART): Consensus Statement
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کلمات کلیدی
ISSMPTHSCTIMIDIFMmSMARTPFs - PF هاprogression-free survival - بقا بدون پیشرفتoverall survival - بقای کلImmunomodulatory drug - داروهای ضد انعقادInternational Staging System - سیستم بین المللی استقرارfluorescence in situ hybridization - فلورسانس در هیبریداسیون در محلFish - ماهیcomplete response - پاسخ کاملHematopoietic stem cell transplantation - پیوند مغز استخوانVAD - چه
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Multiple myeloma is a neoplastic plasma cell dyscrasia that on a yearly basis affects nearly 17,000 individuals and kills more than 11,000. Although no cure exists, many effective treatments are available that prolong survival and improve the quality of life of patients with this disease. The purpose of this consensus is to offer a simplified, evidence-based algorithm of decision making for patients with newly diagnosed myeloma. In cases in which evidence is lacking, our team of 18 Mayo Clinic myeloma experts reached a consensus on what therapy could generally be recommended. The focal point of our strategy revolves around risk stratification. Although a multitude of risk factors have been identified throughout the years, including age, tumor burden, renal function, lactate dehydrogenase, β2-microglobulin, and serum albumin, our group has now recognized and endorsed a genetic stratification and patient functional status for treatment.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mayo Clinic Proceedings - Volume 82, Issue 3, March 2007, Pages 323-341
Journal: Mayo Clinic Proceedings - Volume 82, Issue 3, March 2007, Pages 323-341
نویسندگان
Angela MD, S. Vincent MD, Morie A. MD, Martha Q. MD, Robert A. MD, Philip R. MD, Thomas E. MD, John A. MD, PhD, Stephen J. MD, PhD, Suzanne R. MD, Shaji MD, Steven R. MD, PhD, Fonseca MD, Bergsagel MD, Reeder MD, Stewart MBChB, Roy MD, Dalton MD,