کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3042311 1184808 2006 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel low-grade glioneuronal neoplasm presenting in an octogenarian: Case report and review of the literature
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Novel low-grade glioneuronal neoplasm presenting in an octogenarian: Case report and review of the literature
چکیده انگلیسی

Glioneuronal neoplasms are rare tumors that typically affect patients in the first three decades of life. Since the publication of the World Health Organization (WHO) 2000 classification of tumors, further variants of these tumors have been reported. While most of these lesions are clinically and histologically low grade, aggressive variants have been reported.We present an 83-year-old gentleman who presented with a history of ataxia and weight loss. MRI and CT scan revealed a ring-enhancing bihemispheric lesion in the premotor cortex consistent with a malignant primary brain tumor crossing the corpus collosum. The patient underwent a stereotactic biopsy with drainage of the cystic component. Histopathologic studies revealed a mixed glioneuronal tumor with benign characteristics. A craniotomy was performed and the tumor was resected. Postoperatively, the patient has been followed with serial MRI scans with no evidence of disease recurrence at 27 months.Glioneuronal tumors are extremely uncommon in the octogenarian population, however, it is important to include them in the differential diagnosis of intracerebral masses. They are histopathologically quite heterogeneous, and in this report we present a novel subtype. Radiographically, these lesions can mimic more aggressive primary brain tumors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Neurology and Neurosurgery - Volume 108, Issue 4, June 2006, Pages 426–432
نویسندگان
, , , ,