Validity and reliability of the Portuguese–Brazilian version of the Quality of Life in Epilepsy Inventory–89

ObjectiveThe purpose of this article was to report the translation of the Quality of Life in Epilepsy Inventory–89 (QOLIE-89) into a Portuguese–Brazilian version and evaluate its reliability and validity.MethodsThis study involved 105 outpatients: 54 patients with refractory temporal lobe epilepsy (TLE) with mesial temporal sclerosis (MTS) and 51 with juvenile myoclonic epilepsy (JME). Reliability and test–retest reliability were assessed. Relationships between QOLIE-89 domains and other questionnaires (Nottingham Health Profile, Beck Depression Inventory, Adverse Event Profile, Neuropsychological Evaluation), and external measures such as demographic and clinical variables were analyzed to examine construct validity.ResultsInternal consistency (Cronbach’s α = 0.73–0.92) and test–retest reliability (intraclass correlation coefficient = 0.60–0.84) for individual domains were acceptable. For construct validity, we verified high correlations between the QOLIE-89 and the Nottingham Health Profile, Beck Depression Inventory, Adverse Event Profile, and Neuropsychological Evaluation. For clinical characteristics, the patients with juvenile myoclonic epilepsy had better quality-of-life scores on 11 of 17 QOLIE-89 subscales compared with patients with temporal lobe epilepsy (P < 0.05).ConclusionThese results support the reliability and validity of the Portuguese–Brazilian translation of QOLIE-89.