کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3051047 1185970 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The behavioral consequences of exposure to antiepileptic drugs in utero
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
The behavioral consequences of exposure to antiepileptic drugs in utero
چکیده انگلیسی

The aim of the study was to examine the behavior of 242 children, aged between 6 and 16 years, born to mothers with epilepsy. Exposure to sodium valproate (VPA) in utero was associated with high levels of parental stress induced by the child’s maladaptive behavior. These children were also poorer for daily living skills and skills relating to socialization. The outcomes on both measures were strongly affected by the Full Scale IQ (FSIQ) of the child; however, no significant differences were found between the groups and therefore this pattern of results cannot simply be attributed to a lower FSIQ. The results of this study suggest that exposure to VPA in utero and the presence of a lowered FSIQ are risk factors for the development of poorer adaptive behavior and a higher rate of maladaptive behaviors.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Epilepsy & Behavior - Volume 14, Issue 1, January 2009, Pages 197–201
نویسندگان
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