کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
3051456 | 1185985 | 2006 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Right parietal activation during delusional state in episodic interictal psychosis of epilepsy: A report of two cases Right parietal activation during delusional state in episodic interictal psychosis of epilepsy: A report of two cases](/preview/png/3051456.png)
Magnetoencephalography (MEG) was used to image brain activity associated with delusions in episodic interictal psychosis of epilepsy. Two female patients aged 65 and 68 with temporal lobe epilepsy were studied during and after a delusional state. Topographic images of the excess kurtosis (g2), the statistical index of spikelike activity, were obtained from unaveraged MEG recordings using an analysis called “synthetic aperture magnetometry” (SAM). For both patients, MEG waveforms and excess kurtosis images revealed spiky activity in the right inferior parietal region during the delusional state. A second MEG measurement after delusions were resolved with antipsychotic therapy revealed no excess kurtosis in the right parietal area. Likewise, the sharp waves on MEG recordings disappeared as well. Our results suggest association of the right inferior parietal cortex, including the supramarginal gyrus, with the delusional state of episodic interictal psychosis of epilepsy.
Journal: Epilepsy & Behavior - Volume 9, Issue 2, September 2006, Pages 367–372