کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3066071 1580498 2006 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Acute morphine exposure potentiates the development of HSV-1-induced encephalitis
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Acute morphine exposure potentiates the development of HSV-1-induced encephalitis
چکیده انگلیسی
A devastating consequence of HSV-1 infection is development of HSV-1-induced encephalitis (HSVE). While only a minority of individuals infected with HSV-1 experiences HSVE, clearly defined variables that consistently predict development of the disease remain to be elucidated. The current study examined the effects of a single dose of morphine prior to infection with HSV-1 on the development of HSVE in BALB/cByJ mice. Acute morphine exposure was observed to potentiate the development of HSVE in HSV-1 infected mice. The present data implicate a potential role for the blood-brain barrier in the development of HSVE in morphine-treated mice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Neuroimmunology - Volume 172, Issues 1–2, March 2006, Pages 9-17
نویسندگان
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