کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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3121393 | 1583379 | 2008 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Effect of strontium in combination with fluoride on enamel remineralisation in vitro Effect of strontium in combination with fluoride on enamel remineralisation in vitro](/preview/png/3121393.png)
Previous studies showed that strontium (Sr) as well as fluoride (F) can enhance enamel remineralisation. The aim of this study was to evaluate the effects of Sr in combination with F on enamel remineralisation in vitro. Sixty enamel specimens obtained from caries free human premolars were demineralised to produce caries-like lesions. Half of each lesion was covered with nail varnish as an untreated control. The specimens were then randomly divided into F and Sr + F treatment groups. The F group was exposed to remineralising solutions (1.5 mM CaCl2, 0.9 mM KH2PO4) containing 1 ppm, 0.1 ppm or 0.05 ppm F. The Sr + F treatment group was exposed to the same solutions including 10 ppm Sr. After 2 weeks, lesion depth, mineral loss and percentage enamel remineralisation were determined using transversal microradiography. There was a significant decrease in mineral loss in all groups (p < 0.001). Lesion depth was significantly reduced for all groups (p < 0.05) with the exception of group F. Remineralisation was significantly affected by F concentration (p = 0.000). The participation of Sr resulted in a significant enhancement of remineralisation (p < 0.001) with a synergistic effect of the Sr + F combination (p < 0.01). It was concluded that while the remineralising process was affected by the concentration of F, there was also an interaction between F and Sr when they were used in conjunction.
Journal: Archives of Oral Biology - Volume 53, Issue 11, November 2008, Pages 1017–1022