کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
316645 1432580 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Auditory P300 event related potentials in acute and transient psychosis—Comparison with schizophrenia
ترجمه فارسی عنوان
ظرفیت های مرتبط با رویداد P300 شنوایی در جنون حاد و گذرا: مقایسه با اسکیزوفرنی
کلمات کلیدی
P300؛ روان پریشی های حاد و گذرا. اسکیزوفرنی؛ فیزیولوژی اعصاب
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
چکیده انگلیسی

BackgroundLimited biological research data are available on acute and transient psychotic disorder (ATPD) vis-à-vis schizophrenia. P300 event related potentials (ERP) have been extensively studied as an important neurophysiological parameter in schizophrenia. However, no P300 ERP studies comparing the two disorders are available. We compared auditory P300 ERP in patients remitted from ATPD with schizophrenia in remission and biologically unrelated healthy controls.MethodsIn this case-control study design, 25 subjects remitted from ATPD were age-/gender-matched with healthy controls and patients with schizophrenia in remission. Clinical assessment and auditory P300 ERP (amplitude and latencies at central and parietal sites, reaction time) were recorded. The ERP parameters were compared across the three groups.ResultsAll three groups showed significant differences in P300 amplitudes and latencies at central and parietal sites. Schizophrenia group differed significantly (p < 0.001) from the ATPD group in all the P300 parameters. The ATPD group was found to have lower Pz latency (p < 0.05) and lower mean reaction time (p < 0.001) as compared to healthy controls.ConclusionThe results suggest that P300 could easily distinguish between ATPD and schizophrenia in remission, thus neurophysiologically differentiating the two disorders. Lower P300 latency and reaction time, which indicate hyper-arousability, distinguished ATPD from normal controls, with implications for a better understanding of ATPD.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Asian Journal of Psychiatry - Volume 23, October 2016, Pages 8–16
نویسندگان
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