کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3177390 1200299 2011 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nocturnal Frontal Lobe Epilepsy: New pathophysiological interpretations
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی عصب شناسی
پیش نمایش صفحه اول مقاله
Nocturnal Frontal Lobe Epilepsy: New pathophysiological interpretations
چکیده انگلیسی

Since the first descriptions of Nocturnal Frontal Lobe Epilepsy (NFLE) many theories have been proposed to explain its pathophysiological mechanisms. The aim of this paper is to formulate a tentative hypothesis designed to unify the clinical, anatomo-physiological, and genetic aspects underlying this condition. According to this hypothesis, NFLE is due to a disorder in the thalamocortical circuit involved in the arousal mechanism. Other cortical-networks involving the limbic system may explain, for instance, primitive behaviors. The role of the cholinergic system and related pathways in the pathogenesis of nocturnal seizures and parasomnias is also discussed.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sleep Medicine - Volume 12, Supplement 2, December 2011, Pages S39–S42
نویسندگان
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