کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
321902 539866 2010 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects on cognitive functioning after olanzapine–ziprasidone crossover in recent-onset schizophrenia
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Effects on cognitive functioning after olanzapine–ziprasidone crossover in recent-onset schizophrenia
چکیده انگلیسی

IntroductionTo enhance functional outcome in schizophrenia improvement of cognitive symptoms is crucial.Experimental proceduresUsing a comprehensive test battery, this follow-up examines cognitive effects in patients with recent-onset schizophrenia after a change of medication following insufficient clinical response and intolerance.ResultsAfter eight weeks cognitive outcomes had not improved in the patients having switched from olanzapine to ziprasidone (n = 11; mean dose 136 mg) nor in those having switched from ziprasidone to olanzapine (n = 10; mean 16 mg), while the symptoms of patients maintaining olanzapine (n = 18; mean 10.9 mg) or ziprasidone (n = 18; mean 88.9 mg) treatment had not improved further.DiscussionThe findings suggest that also in early-stage schizophrenia the antipsychotics tested affect cognitive symptoms similarly.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Neuropsychopharmacology - Volume 20, Issue 12, December 2010, Pages 907–912
نویسندگان
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