کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3253958 1207169 2010 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Aproximaciones de terapia génica para la diabetes tipo 1
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
Aproximaciones de terapia génica para la diabetes tipo 1
چکیده انگلیسی
Type 1 diabetes mellitus is a chronic disease characterized by autoimmune destruction of insulin-producing beta-cells. Current insulin replacement therapies offer many patient benefits, but do not prevent secondary complications when glycemic control is insufficient and are associated with the risk of hypoglycemia. Therefore, more efficient and safer therapies are still required. Gene therapy is considered a new approach/tool to treat diabetes. Important advances in the field of gene therapy have made vectors both more efficient and safer in delivering genes to most tissues and cell types. In this review, we first analyze the key issues that should be considered for designing a new gene therapy approach for diabetes and second, we discuss main approaches currently under investigation for this disease. Finally, most relevant results in the field are presented.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Avances en Diabetología - Volume 26, Issue 1, February 2010, Pages 6-12
نویسندگان
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