کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3258935 1207482 2006 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Natural killer cells in human health and disease
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی ایمونولوژی
پیش نمایش صفحه اول مقاله
Natural killer cells in human health and disease
چکیده انگلیسی

Natural killer (NK) cells are lymphocytes of the innate immune system that are critical in host defense and immune regulation. They are activated or inhibited through the ligation of germline-encoded receptors and are involved in mediating cytotoxicity, in producing cytokines and in providing co-stimulation to cells of the adaptive immune system. NK cells play important roles in viral infections, autoimmunity, pregnancy, cancer and bone marrow transplantation. This review highlights recent developments in the understanding of the role of human NK cells in health and disease.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Immunology - Volume 118, Issue 1, January 2006, Pages 1–10
نویسندگان
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