کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
3271077 1208259 2010 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A Hip Analysis Protocol for Pediatric Bone Densitometry: The Iowa Bone Development Study
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی غدد درون ریز، دیابت و متابولیسم
پیش نمایش صفحه اول مقاله
A Hip Analysis Protocol for Pediatric Bone Densitometry: The Iowa Bone Development Study
چکیده انگلیسی
Pediatric proximal femur dual-energy X-ray absorptiometry (DXA) scans present analytic challenges because of the lack of standard points of reference in the growing skeleton. The Iowa Bone Development Study (IBDS) developed a modified pediatric-specific proximal femur analysis protocol using Hologic software. Serial DXA measurements were obtained for 214 children at approximate ages 5, 8, 11, and 13 yr. Standard analysis procedures as described by the manufacturer (Hologic default) were compared with the IBDS protocol. The IBDS protocol yielded lower but more stable results for bone area, bone mineral content (BMC), and bone mineral density for total hip, femoral neck, trochanter, and intertrochanter as a result of more precisely controlling the regions of interest. Linear regression models with body size, age, and gender as predictors were developed to examine variation in measurements. Coefficients of determination (R2) with the IBDS protocol were greater for each time point, demonstrating that the modified protocol was better aligned with body size. Similarly, Spearman correlation coefficients between total hip and hip subregions were consistently higher for BMC and bone area with the IBDS protocol with differences more notable among younger children. The IBDS protocol provides a reproducible method for evaluating pediatric proximal femur DXA scans during growth.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Densitometry - Volume 13, Issue 4, October 2010, Pages 361-369
نویسندگان
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